GI Archives

IR Micro-Endoscope to See Underneath Epithelium

WiOptixFounder IR Micro Endoscope to See Underneath EpitheliumUniversity of Florida Researcher Huikai Xie is working on an endoscopic imaging technique using a tiny infrared scanning technology that, when placed near the surface of a tissue, moves rapidly back and forth to not only provide high resolution images of epithelial tissue, but also peer immediately underneath it.
Xie and his team have already published forty papers on the research and recently founded WiOptix, Inc. to try and commercialize the technology. His vision is not only to augment and/or supplement a traditional endoscope, but to merge the technology with cutting tools for surgical use, so that “when surgeons begin cutting, they know exactly what’s in front of them.”
From the University of Florida press release:

Xie’s endoscopes replace the cameras with infrared scanners smaller than pencil erasers. The heart of his scanner is a microelectromechanical system, or MEMS, device: A tiny motorized MEMS mirror that pivots back and forth to reflect a highly focused infrared beam.
By itself, the beam only strikes a period-sized dot of tissue. But the MEMS mirror allows it to move methodically back and forth, scanning a fingernail-sized piece of tissue row by row, like a lawnmower moving across a yard. The resulting image is high resolution: Xie said his scanners have achieved resolution of 10 microns, or 10 millionths of a meter, in laboratory tests. That’s more than 10 times higher resolution than the only other non-camera-based endoscopes on the market, which use ultrasound technology, he said. The high-resolution image also includes depth information, so the risky biopsy can be more specific to avoid randomness, or even completely avoided. WiOptix IR Micro Endoscope to See Underneath Epithelium
Computers process the return signal from the endoscopes, transforming it into a three-dimensional image of the surface tissue and the tissue beneath. One scanner even produces a 360-degree-image of all the tissue surrounding the endoscope. Doctors or other trained observers can then search the image for abnormalities or suspicious growth patterns.

Press release: Engineer designs micro-endoscope to seek out early signs of cancer…
WiOptix technology page…

EndoBarrier May Be Helpful in Patients With Type II Diabetes

EndoBarrier May Be Helpful in Patients With Type II Diabetes

Clinical researchers from Hospital Dipreca in Santiago, Chile, Gastro Obeso Center in São Paulo, Brazil, Carolinas Medical Center in Charlotte, North Carolina, and the Billings Clinic in Billings, Montana conducted a multi-center study of the EndoBarrier gastrointestinal liner from GI Dynamics (Lexington, Massachusetts) on patients with type II diabetes. The trial demonstrated overall positive results, and Dr. Robert Jasmer from UCSF reviewed the findings of the study at MedPageToday.
A snippet:

Read More

SmartPill Receives Expanded Indication in US

SmartPill Receives Expanded Indication in US

The FDA has given the go ahead to SmartPill (Buffalo, NY) to market version 2 of the firm’s device for evaluation of constipation. The device measures temperature and pH as it moves through the GI tract, and provides temporal-spacial analysis of its voyage. The system was already approved for analysis of suspected delayed gastric emptying (gastroparesis).

The SmartPill GI Monitoring System, version 2.0, allows physicians to measure pH, pressure and temperature throughout the entire gastrointestinal (GI) tract, providing whole gut and regional gut (gastric, small bowel and colonic) transit times, a pH profile of the entire GI tract and GI tract pressure patterns. SmartPill’s ability to differentiate slow (abnormal) transit from normal transit, while providing regional transit times for both the upper and lower GI tract, is an important assessment for physicians when evaluating GI motility disorders and guiding appropriate therapy.

Read More

Mederi Tries to Solve a Tricky Marketing Challenge

Mederi Tries to Solve a Tricky Marketing Challenge

Mederi Therapeutics out of Greenwich, Connecticut offers an radiofrequency therapy system designed to treat fecal incontinence. Not surprisingly, this is a topic that patients rarely bring up due to embarrassment, and the consequence is an untreated condition that can severely impact the quality of life. MassDevice spoke to William Rutan, CEO of Mederi, about the challenges of operating in such a market and what the company learned from the marketing efforts of pharmaceutical firms selling erectile dysfunction drugs.
A snippet from the interview:

Read More

Swallowable Robot Carefully Crawls Through The GI

The BBC is reporting on a wirelessly controlled “spider pill” being developed somewhere in Italy. The device supposedly has eight legs and reportedly can crawl through intestines. With an attached video camera, the device might actually become a diagnostic modality for imaging the intestinal tract. The big question is whether it is more unpleasant to have a colonoscope defile you or a robotic gerbil crawl through the insides.

Link @ BBC

Read More

Boston Sci Wins Biliary Stent Approval by FDA

Boston Sci Wins Biliary Stent Approval by FDA

Boston Scientific just announced FDA approval of the WallFlex Biliary RX fully and partially covered stents “for the palliative treatment of malignant bile duct strictures.” The device has already been approved in Europe and now it will be available on both continents.

The WallFlex Biliary RX Stent is designed to offer the benefits of prior-generation stents, such as the industry-leading WALLSTENT(®) Endoprosthesis, while incorporating new features to accommodate a range of anatomical and clinical requirements. Based on extensive research and physician feedback, the WallFlex Biliary RX Stent employs a platinum-cored Nitinol construction designed to deliver on three critical components: radial force, flexibility and radiopacity. The Platinol™ Wire provides greater flexibility – 30 percent more than the WALLSTENT Endoprosthesis – to help the stent conform within tortuous anatomies. The enhanced full-length radiopacity offered by the Platinol Wire and the reconstrainable delivery system are designed to allow for more precise stent placement, while the radial force of the WallFlex Biliary RX Stent is designed to maintain patency and resist migration….

Read More

PillCam SB Gets Expanded Indication in US

PillCam SB Gets Expanded Indication in US

Given Imaging out of Yoqneam, Israel has received FDA clearance to market the firm’s PillCam SB video capsules and the accompanying Agile pills for children two years of age and older. The PillCam SB is a swallowable video device meant for imaging of the small intestine onto an embedded memory chip and Agile is a supporting product for testing the gastrointestinal tract for clear passage of the PillCam.

– PillCam SB is used by physicians to evaluate patients and detect small bowel abnormalities, such as obscure GI bleeding, iron deficiency anemia, suspected Crohn’s disease, suspected small intestinal tumors, polyposis syndromes, as well as in suspected or refractory malabsorptive syndromes, such as celiac disease.

Read More

F&S Awards Crospon for GERD Test Device

F&S Awards Crospon for GERD Test Device

Crospon, out of Galway, Ireland, recently received Frost & Sullivan’s 2009 European Gastroenterology Technology Implementation of the Year Award for the Endoflip device. The Endoflip delivers a balloon catheter to the gastroesophageal sphincter, a junction between the esophagus and stomach, and can test the strength of the muscles controlling its closure. Already approved in the EU, the company is seeking FDA’s approval for the US market.
From the manufacturer:

Read More

Cook Introduces “High Definition Endoscopic Ultrasound” Technology Needle

Cook Introduces "High Definition Endoscopic Ultrasound" Technology Needle

Cook Medical has released a new needle for endoscopic ultrasound guided biopsies that promises to be three times brighter that other available needles. The company believes the system, designed to be used in conjunction with the EchoTip Ultra delivery device, that is compatible with most endoscopes, will deliver a better biopsy precision.

During an EUS procedure, the endosonographer inserts an endoscope, which has a small ultrasound transducer at its tip, through the patient’s mouth into the esophagus, facilitating imaging from within the GI tract. EUS also enables tissue sampling through fine needle aspiration (FNA), a safer and less invasive alternative to open surgical biopsy. Under ultrasound guidance, a special needle inserted in the endoscope collects cells from targeted sites.

Read More