Ever since the Danish bacteriologist Hans Christian Gram developed his eponymous test (the Gram stain) in 1882 to differentiate between types of bacteria, diagnostic tests have been integral to both public and individual health. The ability to rapidly and accurately detect microbes is becoming increasingly important given the emergence of diverse drug resistant strains, such as Methicillin-resistant Staphylococcus aureus (MRSA; Gram positive bacteria resembling purple grapes), as well as the length of time it currently takes to diagnose and treat certain infections (e.g. Mycobacterium tuberculosis, which cannot be detected via Gram stain but rather an acid-fast stain, has an incredibly slow doubling time which is why it can take weeks to accurately diagnose tuberculosis). In recent years genomic technologies have fortunately opened the doors for faster and more accurate detection of microbes than petri dish cultures and chemical staining can provide. Medgadget had the opportunity to interview two partner companies – PathoGenetix and Sagentia – that are developing a state-of-the-art Genome Sequence Scanning (GSS) technology, which promises to bring rapid microbial detection to the fields of microbial genomics research, food and product safety, and clinical infectious disease testing.
Shiv Gaglani, Medgadget: How many micro-organisms can be detected through the partnership technology?
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