Archives: 12/2011

f2f7878345d Radio Spectrum Allocated for Devices to Activate Paralyzed MusclesThe FCC has kindly allocated a chunk of radio spectrum in the 413-457 megahertz range specifically for use by wireless devices that would relay nervous signals to paralyzed limbs.

According to Bloomberg, The Alfred Mann Foundation is planning on beginning trials of technology utilizing this band to help people with head and neck cancer who have difficulty swallowing and brain injury patients with arm paralysis.

From FCC’s press statement:

Medical Micropower Networks (MMNs) are ultra-low power wideband networks consisting of multiple transmitters implanted in the body that use electric currents to activate and monitor nerves and muscles.

As the FCC also recognized in the 2010 National Broadband Plan, wireless technology can improve the quality of life for individuals and lower the cost of health care. Today’s action advances this broadband health care agenda.

The FCC initiated this proceeding in response to a petition from the Alfred Mann Foundation, which has built prototype MMN systems and conducted extensive testing that demonstrates that this new medical technology can reliably operate in shared spectrum to deliver vital therapies. The action the FCC takes today will allow devices such as those being tested by Alfred Mann to proceed on the path to patient use as well as inspire researchers to begin work on the next generation of implanted medical radio networks.

Link: FCC TAKES STEPS TO INTRODUCE NEW ADVANCED MEDICAL TECHNOLOGIES TO TREAT NEUROMUSCULAR DISORDERS AND TRAUMATIC INJURIES

More at Bloomberg: Medical Devices That Help Paralyzed Move Will Get Radio Spectrum

lo5go e22s Medgadget en EspañolWe’d like to remind our Spanish speaking audience that all of our articles are professionally translated and available in Spanish on our sister site Medgadget.es  There you can also subscribe to the Medgadget.es Twitter, RSS, Facebook, and Mobile feeds and keep up with the latest medical technology in your mother tongue.

Link: Medgadget.es

In a fascinating presentation, Gabor Forgacs of Organovo spoke at the last TEDMED about tissue printing technology his company is working on. Organovo is currently in the process of commercializing vessel printing for biomed research, and hopes one day to move on to organ printing and even the manufacture of synthetic meat.

Later in the day, Gabor actually brought some printed meat with him for a fun little demo. Here’s from our coverage of TEDMED 2011:

gabor meat The Art and Science of Tissue PrintingIn a hilarious and aptly timed demonstration, Gabor Forgacs from Organovo got on stage next to talk about printing meat with his tissue printers. He had talked previously about using them to regenerate tissue for human health, but it is equally possible to take muscle cells and print them for human consumption. He brought up a little frying pan, opened up a vial, and pulled out a strip of “printed” pork that he made using his technology, heated it, and ate it right in front of us. The whole spectacle was hilarious and the audience was loving every moment. He’s not sure what to call his new type of meat but is leaning toward “lab meat” or “in vitro meat.”

TEDMED 2011 flashbacks: Day 1 – Pop It, Lock It, and Take a Statin; Day 2 – Glow in the Dark Tumors that Blind Rats Can Now See; Day 3 – Mushroom Loving Insects and FDA Blues; Day 4 – Nano Shapes and Confronting Death

tg3g354g43242 Esaotes Latest Ultrasound Devices Coming to Market

Esaote is releasing two new ultrasound systems for general clinical use.

go0o848475 Esaotes Latest Ultrasound Devices Coming to MarketThe MyLab Seven is a traditional wheeled device in a small footprint with new productivity features and the MyLab Alpha is a miniaturized laptop-like ultrasound that brings the same high quality imaging of the company’s high end systems into a small package.

From the announcement:

The innovative POP platform is the core of the new MyLabTM systems and delivers ease-of-use, applicationspecific customization and new levels of connectivity. The systems offer a simple and user-friendly interface, a wide LCD HD display screen, outstanding attention to ergonomic detail and an intelligent touch-screen which features Esaote’s exclusive e-touch technology.

The e-touch feature represents Esaote’s pioneering approach to take exam efficiency to a new level. By simply pressing the e-touch button, a user can now enter a customized environment where personal settings, complex functions, annotations and measurements can be stored and easily recalled during the examinations, allowing a standard ultrasound system to become someone’s personal diagnostic tool.

MyLabTMSeven and MyLabTMAlpha also offer advanced connectivity technology, including wireless networking, full DICOM and IHE compliance. MyLabTMDesk, Esaote’s software that allows users to archive, review, post-process and print exams from the convenience of a PC, is also available to increase productivity.

Press release: Esaote Introduces its Revolutionary Productivity-Oriented Platform with the Debut of its MyLabTMSeven and MyLabTMAlpha Ultrasound Systems

Expander wDosageController AeroForm Breast Tissue Expanders Now Being Implanted in IDE Trial
Breast reconstruction following a mastectomy can be a painful and generally unpleasant experience that requiresBodyForm Final AeroForm Breast Tissue Expanders Now Being Implanted in IDE Trial office visits for regular saline injections that pump up the implanted expander. AirXpanders out of Palo Alto, CA has announced that the first patient has been enrolled in an IDE trial of its AeroForm technology that allows women to control the expansion of the implant on their own using a remote control.

AeroForm implants contain a CO2 cartridge connected to a wireless controller that regulates how much gas is let out into the expander. Under normal circumstances the gas is let out in a slow continuous stream, but the patient can make changes to the rate of the expansion.

It’s hard to avoid the obvious possibility of such technology one day reaching the aesthetic plastic surgeon’s office and women being able to “adjust” to the dress they’re wearing.

Press release: AirXpanders Announces First Patient Treated in IDE Trial of New Post-Mastectomy Tissue Expansion Device

Product page: AirXpanders AeroForm

Trial info page: Patient Controlled Tissue Expansion for Breast Reconstruction (XPAND)

Flashback: Tissue Expansion System for Breast Reconstruction Receives FDA Investigational Device Exemption

bml48k5v Lab on a TouchScreen Might Make Smart Phones into Pathology LabsWe at Medgadget have been covering an increasing number of lab-on-a-chip (LOC) technologies over the last number of years. Many of these existing LOC devices consist of a microfluidic cartridge containing reagents which typically needs to be analyzed by larger bench top devices. Recently, researchers from the Korea Advanced Institute of Science and Technology have come up with an interesting low-cost concept for performing these analyses using the touchscreen of a smartphone.

The researchers’ approach takes advantage of the capacitive nature of the touchscreen. Most modern touchscreens are large arrays which store electrostatic charge across their capacitive layers. When another electrical conductor, such as a human finger, comes into contact with the screen, the electrostatic charge is disturbed and a contact point is registered. By applying a bio-sample such as blood, saliva, or even urine from a LOC cartridge to the screen, the researchers hope to register specific changes in the screen’s capacitance which is indicative of the contents of the sample. In this way an app on the phone could perform the analysis and report the results.

To date the researchers have demonstrated a proof of concept which was published in the journal Angewandte Chemie International Edition at the end of October. They demonstrated that their touch-screen analysis was capable of distinguishing between solutions containing three different concentrations of DNA sourced from the bacteria that causes chlamydia using only 10 micro-liter samples.

The technology is currently unable to detect pathogens, but the ability to distinguish between sample concentrations would appear to be a significant first step. Of course a number of issues exist, namely the need to apply the sample to your phone’s screen. For the moment however, we think we’ll stick with more conventional sampling methods.

Abstract in Angewandte Chemie International Edition: A Touchscreen as a Biomolecule Detection Platform

l7d573mi Wired Feature: Apple’s Secret Plan to Steal Your Doctor’s HeartWired is featuring a lengthy write-up about the use of iPads by doctors and other clinical staff in hospitals. It starts by introducing Afshad Mistri, Apple’s medical market manager, then moves on to discuss the different uses of iPads by doctors and finishes by explaining why Apple is specifically targeting doctors. A recommended read for anybody interested in the use of iDevices in medicine.

Wired: Apple’s Secret Plan to Steal Your Doctor’s Heart…

Digital ArtForms has launched iMedic3D, a pair of 3D mice for the navigation of 3D medical image data from modalities such as CT or MRI. Combined with a software viewer, it allows the user to immerse himself and navigate the 3D data in a more natural way.

We took the opportunity to catch a demo of their iMedic3D system to bring to you:

More from the press release announcing the system:

iMedic3D is a DICOM visualization application that immerses clinicians in their 3D data. It’s powered by Digital ArtForms Two-Handed Interface (THI), a powerful object and viewpoint manipulation technology that lets users almost instantly position themselves anywhere in their data, looking in any direction, and at any scale. iMedic3D’s decluttering tools give users easy access to features embedded in cluttered or solid datasets. In a study funded and overseen by the US Army’s Telemedicine and Advanced Technology Research Center (TATRC) THI was shown to be 4-5 times as fast as a mouse in the hands of novices (47 minutes of training) and approaching 9 times the mouse in the hands of experienced users in the performance of fundamental 3D tasks. iMedic3D is available today without FDA clearance.

Press release: Digital ArtForms Debuts iMedic3D, a Radically Different Approach to Radiology, at RSNA ‘11…

Company homepage: Digital ArtForms…

m5ssui1l Researchers Non Invasively Monitor Nanotubes in Live Cells, Blood Researchers at Purdue have developed a method of monitoring both metallic and semiconducting nanotubes within cells and blood plasma without using any kind of marking or dying labels. The method, called transient absorption, uses two near-infrared lasers to energize and detect the shining nanotubes.

The method should be useful for monitoring the effects of nano-based treatments during laboratory and clinical development.

The nanotubes have a diameter of about 1 nanometer, or roughly the length of 10 hydrogen atoms strung together, making them far too small to be seen with a conventional light microscope. One challenge in using the transient absorption imaging system for living cells was to eliminate the interference caused by the background glow of red blood cells, which is brighter than the nanotubes.

The researchers solved this problem by separating the signals from red blood cells and nanotubes in two separate “channels.” Light from the red blood cells is slightly delayed compared to light emitted by the nanotubes. The two types of signals are “phase separated” by restricting them to different channels based on this delay.

Researchers used the technique to see nanotubes circulating in the blood vessels of mice earlobes.

The researchers also have taken images of nanotubes in the liver and other organs to study their distribution in mice, and they are using the imaging technique to study other nanomaterials such as graphene.

Link @ Purdue: ‘Label-free’ imaging tool tracks nanotubes in cells, blood for biomedical research

Abstract in Nature Nanotechnology: Label-free imaging of semiconducting and metallic carbon nanotubes in cells and mice using transient absorption microscopy