Archives: 6/2011

87598grt GE, Mayo Clinic Working on Dedicated Head MRI
GE and Mayo Clinic have received a nearly $6 million NIH grant to research a standalone MRI machine dedicated to scanning of the brain.  The research would focus on both the development of the device and how it would be implemented in a clinical setting.  Because up to a third of all MRI scans today are performed on the brain, a dedicated stand-alone unit that is smaller and cheaper may help improve clinical outcomes and be more cost efficient.

The intention is that a dedicated high-field scanner could offer a more specialized imaging approach and a greater range of functionality for neurological imaging compared to the current one-size-fits-all concept of whole-body MRI imaging. The goal of the program is ultimately to understand and address the technical issues involved in dedicated MR imaging of the brain.

This NIH-funded collaboration between GE and Mayo Clinic illustrates an emerging trend of more specialized imaging systems. With a dedicated approach, MRI scanners can be more specifically tailored and designed for neurological imaging applications that potentially lead to improved image quality and a more comfortable experience for the patient. It will also potentially enable smaller, lighter designs that increase the accessibility of MRI to remote settings and regions where the technology is currently unavailable. The project is closely aligned with GE’s healthymagination initiative, which is built on a global commitment to reduce costs, improve quality and expand access to healthcare for millions of people.

Compared to equivalent field strength whole-body MRI scanner, GE’s prototype scanner will be designed to deliver the same (or better) quality images, but from a scanner that is only one-third the size and significantly lighter.

Beyond removing major siting barriers, GE researchers will be incorporating new image analysis tools and easier-to-use operating systems and interfaces that expand the system’s imaging capabilities and would enable more healthcare professionals to acquire diagnostic images. For example, new “one-touch” features are being developed that will simplify the programming of image settings from dozens of complex inputs to a single control.

Link: GE Researches Dedicated MRI Brain Scanner Technology …

TEMPASURE ACT’s TEMPASURE for Atrial Arrhythmias Wins European ApprovalAdvanced Cardiac Therapeutics, Inc. has received the European CE Mark for its TEMPASURE cardiac ablation catheter.  The device is capable of measuring local temperature of the treatment area, helping prevent overheating, while delivering saline irrigation.

The TEMPASURE system is designed to result in better outcomes for patients by reducing overall procedure time and increasing therapeutic effectiveness, while avoiding rare but serious adverse events that can occur with current technologies. The system’s novel passive sensing microwave radiometry technology allows the electrophysiologist to measure the temperature of cardiac tissue during the ablation procedure, providing real-time information that enables proper energy delivery and lesion control. This technology is designed to allow, for the first time, safe and effective automatic RF power titration or “Temperature Mode” irrigated ablation.

The introduction of saline irrigation to catheter ablation yielded a number of positive benefits, but one of the disadvantages of saline irrigation was the loss of temperature feedback. Today, most clinicians use power settings to drive ablation creation. The clinical issues that arise from this approach are two-fold: 1) lesion quality is poorly understood because it is impossible to know if the ablation is merely stunning the tissue or reaching the required temperature (specifically at depth) to effectively ablate the heart wall tissue and 2) current ablations pose a safety risk because there is no determinable way to know when you have reached the desired temperature – and the risk of overheating remains.

The TEMPASURE™ cardiac ablation catheter enables for the first time knowledge of temperature measurement at 3 mm depth and saline-irrigation. VERITAS™ Technology, a proprietary microwave radiometry system, continually reads the temperature 3 mm below the heart wall surface providing EP Physicians with greater control and real-time, more accurate information regarding validation of lesion creation and completeness. Finally – a catheter that provides information previously believed to be unattainable.

Press release: Advanced Cardiac Therapeutics Announces CE Mark Clearance For Innovative Catheter System for the Treatment of Atrial Arrhythmias …

Product page: TEMPASURE…

Flashbacks: TEMPASURE Cardiac Ablation Catheter Measures Temperature of Treated Tissue

fvbd957k Fraunhofer Develops 3D Herpes Model to Test Potential TreatmentsApproximately 90 percent of people are carrying the herpes simplex virus, but the virus spends most of its time in a dormant state which has proven difficult to research. Now, scientists at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have developed a 3D herpes infection model which they are now using to study the virus’ dormant state. The investigators claim their research will aid in the testing of future cold sore treatments by reducing the need for animal testing.

From the press release:

To date the skin models used for drug testing and to detect the virus have been very simple and unable to simulate the dormancy state of the virus. “We have integrated a neuronal cell line into the certified skin model of the IGB and are able to detect this latency stage for the first time.”

Research on active ingredients can profit from the 3D herpes infection model of the researchers from IGB, a model that also enables improved study of infection mechanisms. This procedure might also be used to test new medications for shingles, which is also caused by a variant strain of the herpes virus.

Full story: Goodbye cold sores…

zdpc2bk51 MedeGrip Given Go Ahead in EuropeMedeGrip, a simple foam device for working with small or breakable things in the clinic or on the floor, has received the European CE Mark of approval.  It was less than a month ago that MedeGrip was successfully registered with the FDA as a Class 1 device and Access Scientific included it as part of the POWERWAND Maximum Barrier Kit.

Developed by a PICC line nurse, the device helps take away the pain of handling things like Luer Loks and pin knots, and makes it a bit safer to work with glass ampules.

Here’s a short video demonstrating the MedeGrip:

Product page: MedeGrip…

Flashbacks: MedeGrip to Make Work With Central Lines, Ampules, Other Devices Easier and Safer; MedeGrip for Pain Free Fingers Gets FDA Registered

v2wdjj Philips New Budget Conscious PET/CT With Time of Flight Technology
Philips has introduced its Astonish TF Time-of-Flight (TOF) technology into its new budget PET/CT scanner, the TruFlight Select, and will be making TOF a standard on the company’s entire PET line.  0jdjj Philips New Budget Conscious PET/CT With Time of Flight TechnologyBy using intelligent timing, Astonish TF pinpoints the location of events with greater precision, leading to what the company claims is an up to 30% greater contrast resolution compared with non-TOF equipped systems.

From the announcement:

TOF technology for positron emission tomography (PET) scanners is designed to enhance image quality by reducing image artifacts and providing higher sensitivity. The resulting images help clinicians better detect and locate lesions to increase diagnostic confidence and preserve healthy tissue during treatment. According to a recent study, TOF scans can help to improve lung and liver lesion detectability. In the study the improvement was more pronounced in heavy patients.

Compared to non-TOF systems, Astonish TF allows for up to 30 percent improved contrast resolution while maintaining quantitative accuracy. With 495 picosecond timing resolution on all new systems, Philips provides the fastest timing resolution of all currently available PET systems with TOF. Philips now offers TOF technology for virtually all budgets and clinical needs.

All Philips TOF PET/CT systems that have been purchased since 2006 can be upgraded to the latest version of Astonish TF for improved performance.

fu3usj Philips New Budget Conscious PET/CT With Time of Flight Technology

Press release: Philips Announces the First Economical TOF PET/CT System and Standardization of Astonish TF Across its Time-Of-Flight Portfolio …

Product page: TruFlight Select PET/CT…

vn3iosj Australian Researchers Develop Color Changing Bandage

Louise van der Werff, a Ph.D. student from Monash University in Melbourne, Australia, has created a bandage that changes color in response to changes in heat. Looking somewhat like a giant mood ring, the psychedelic bandage is made up of special thermochromatic fibers that can detect changes in temperature as small as half a degree Celsius. Since inflammation or problems with blood supply at the wound site can cause an increase in temperature that can lead to an infection, a quick and accurate diagnosis is necessary. The color-changing bandage holds many advantages over the most common method of using electronic instruments in that it requires no electricity, gives a near-instant measurements, and costs less. Moreover, as the thermochromatic fibers can change to a wide range of colors, physicians can match the color of the fibers with a calibrated chart. Groovy!

Article from Monash University: Heat sensitive bandage could combat infection….

(hat tip: Fresh Science)

8d3u Cook Medicals Ultrasound Biopsy Needle Provides Greater Accuracy in Diagnosing GI CancersResults from a multicenter European study, that was presented at at the 2011 Digestive Disease Week conference, indicate that Cook Medical’s 19-gauge EchoTip ProCore High Definition Ultrasound Biopsy Needle can aid gastroenterologists in diagnosing multiple types of cancers in a variety of target tissues with a high degree of accuracy.

A company representative tells Medgadget that this new, large-core biopsy needle “designed for use with an endoscopic ultrasound (EUS) scope may help to overcome limitations of current EUS methods for biopsies of lesions in the gastrointestinal (GI) tract and surrounding tissue. The EchoTip ProCore needles obtain intact tissue samples, allowing for a histological diagnosis rather than conventional cytological diagnosis based on individual cells. In addition to this advantage, the needles are designed to access difficult-to-reach tissue in areas of the GI tract such as the pancreatic head.”

More from the press release:

EUS is an established procedure for diagnosing GI cancers and determining the stage of their development. Most often, a very fine needle is used—but fine-needle aspiration (FNA) can have limited yield and sensitivity for certain kinds of tumors or in some anatomical locations and only procures a cytological sample.

The EchoTip ProCore needles circumvent this limitation by obtaining intact tissue samples, allowing for a histological diagnosis rather than conventional cytological diagnosis based on individual cells. In addition to this advantage, the needles are designed to access difficult-to-reach tissue in areas of the GI tract such as the pancreatic head.

In the five-center study to be published in Gastrointestinal Endoscopy, the 19-gauge EchoTip ProCore retrieved adequate histological tissue samples in 89.5 percent of cases, and subsequent diagnosis proved accurate in more than 85 percent of total cases. The overall accuracy for detecting malignancy in EchoTip ProCore samples was greater than 92 percent. Moreover, 78 percent of the samples were collected with just one pass of the needle; in FNA, the recommended number of passes can be as high as seven. Researchers studied 109 patients with 114 intestinal lesions and/or peri-intestinal lymph nodes.

Features from the product page:

  • Specially designed needle-tip to increase sampling yield and promote collection of histological core samples
  • High-definition dimpling pattern provides exceptional needle visibility
  • Naturally contoured handle delivers precise needle control and stability
  • 8 cm needle extension affords a large diagnostic reach
  • Safety lock ring easily slides and locks at the desired extension
  • “Zero” reference mark ensures complete needle retraction within the sheath
  • Supplied sterile. Disposable; intended for single use only

Press release: Biopsy Needle Provides Advanced Accuracy in Diagnosing Cancers of GI Tract …

Product page: Echotip ProCore High Definition Ultrasound Biopsy Needle …

convatec ConvaTec Announces Improved, Thinner Versiva XC DressingConvaTec (Skillman, NJ) has announced a thinner version of its Versiva XC dressing which will better conform to the patient’s body. Versiva XC dressing incorporates the company’s Hydrofiber technology, which helps trap fluids, removing bacteria from the wound site and helping maintain an ideal moisture balance.

From the press release:

The new and improved Versiva® XC® dressing includes a thinner layer of adhesive, making it 40% more conformable at its border. Greater conformability is designed and intended to improve flexibility, which may enhance patient comfort. The dressing was developed based on feedback and collaboration with clinicians and nurses who use adhesive dressings to help promote wound healing.

Because Versiva® XC® is thinner, it also represents a more discreet dressing option that can improve patient confidence that the dressing will remain in place and is designed to support improved healing, healthy periwound skin and increased comfort.

Press release: ConvaTec Introduces Thinner Versiva® XC® Dressing Designed to Improve Conformability

Product pages: Versiva® XC® Gelling Foam Dressing with Hydrofiber® Technology; Hydrofiber® Technology

72rhsd AngioDynamics New NeverTouch 1470nm LaserAngioDynamics has expanded its VenaCure EVLT product line for treatment of varicose veins with a new 1470nm laser. This is the first 1470nm wavelength laser of its kinds to feature a gold tip jacket.

The innovation behind the NeverTouch tip is a glass weld at the distal tip of a 600 um fiber. This weld results in an effective fiber diameter of 905 ums and lowers the actual power density by 56 percent from that of a standard bare-tip 600 um fiber. The net effect is a homogeneous ablation with less focal charring of the vein wall than that which is seen with bare-tip fibers.NeverTouch AngioDynamics New NeverTouch 1470nm Laser

AngioDynamics’ patent- pending technology is different from competitors with standard covered-tip fibers that have the same power density as a 600 um fiber.

The proprietary technology maximizes tip visibility under ultrasound and eliminates chances of inadvertent fiber tip contact with the vein wall, further improving safety and patient comfort.

Press release: AngioDynamics Launches VenaCure® 1470nm Laser for Treatment of Varicose Veins …

Product page: VenaCure® 1470 Laser …

Flashbacks: AngioDynamics’ New 90cm VenaCure EVLT Kit ; AngioDynamics Adds New Access Kit to its VenaCure EVLT System