Archives: 4/2011

1277815404778.high resolution crop Medtronics Enlite Sensor Provides Improved Comfort for Continuous Glucose Monitoring Patients
Medtronic has announced CE marking and the pending launch of its new Enlite sensor for use with the company’s continuous glucose monitoring (CGM) systems. The Enlite has demonstrated better accuracy than Medtronic’s previous CGM sensors, and provides greater patient comfort due to its smaller profile. CGM has proven more effective than manual finger-prick testing at enabling patients to manage their blood sugar, and Medtronic hopes that the Enlite’s improved comfort will lead to greater adoption of CGM. The new sensor is designed for use with Medtronic’s MiniMed Paradigm REAL-Time System, MiniMed Paradigm Veo System, Guardian REAL-Time Continuous Glucose Monitoring System, and the iPro2.
From the press release:

Significant design improvements make Enlite Sensor more comfortable and easier to use than the previous sensor. In a clinical study of Enlite Sensor, 85% of patients agreed that sensor insertion was pain free and 86% agreed that the Enlite insertion device was easy to use. The Enlite Sensor is a significantly smaller sensor compared to Medtronic’s previous product – 69% smaller in sensor size by volume, 38% shorter in length. Adding to patient convenience, the Enlite Sensor can be worn on the abdomen and buttocks and used for up to six days.

Press release: Medtronic Launches More Accurate and Comfortable Sensor to Help Improve Glucose Control…

7q3yhs Johns Hopkins Guides on Unbound Mobile PlatformJohns Hopkins University has chosen Unbound Medicine as the official electronic publisher of its Antibiotic (ABX), Diabetes, and HIV POC-IT Guides. The guides provide evidenced-based information that is regularly updated so they stay on top of the latest clinical knowledge.

Using Unbound’s web-based content management system, uPub™, expert editors at Johns Hopkins are able to write, edit, and review, easily updating a single XML content repository containing the ABX, Diabetes, and HIV Guides in a customized workflow. Unbound then uses the platform to publish the latest version directly to the website and mobile devices including iOS (iPhone®, iPod touch®, iPad™), Android™, BlackBerry®, and Windows Phone®.

Press release: Unbound Medicine and Johns Hopkins Publish Point-of-Care Resources…
Link: Johns Hopkins Guides…

jsdr5 PatientsLikeMe Now Open to AllThe popular networking site PatientsLikeMe is finally opening its doors to people with any medical condition. Until now only patients with 22 chronic conditions were able to participate in the site’s communities, setting the stage for a wider roll-out. PatientsLikeMe also created an interesting graphic showing the pattern of connections patients make on the site in a given day.
From the announcement:

Since launching in 2006, members of the website have shared data on more than 9,700 treatments and 4,800 symptoms related to their chronic conditions. During that time, PatientsLikeMe also received requests from 23,000+ patients asking the company to “build a community” for more than 5,000 conditions, everything from the more commonly known conditions like rheumatoid arthritis, autism, diabetes and cancer to rare diseases like ankylosing spondylitis and Niemann-Pick disease.

Company’s press statement: PatientsLikeMe.com Calls All Patients With Any Condition to Join…
Link: PatientsLikeMe…

8ig2odu4 SMARTPATCH May Soon Reduce Post Stroke Shoulder PainMedCity News is reporting that SPR Therapeutics of Cleveland, Ohio is close to receiving FDA regulatory approval for its SMARTPATCH Peripheral Nerve Stimulation System aimed at treating shoulder pain in patients post stroke. The device utilizes percutaneous leads to stimulate muscle activity and in turn reduce pain.
From MedCity News:

Clinical trials have shown that the device works, and SPR has submitted a 510(k) application to the U.S. Food and Drug Administration that, if approved, would clear the company to begin selling the device.
Additionally, SPR will pursue regulatory clearance for more clinical indications, such as general shoulder pain and lower back pain. A fully implantable version of the device, which will require following the FDA’s more onerous and lengthy Premarket Approval Application process, is planned for commercialization in about five years.

More from MedCity News: Neurotech startup SPR Therapeutics readies for launch of pain relief device…
Product page: SMARTPATCH…

aq4u5uj Overnight Pulse Oximetry Able to Provide Cardiovascular Risk Assessment
A study published in journal Chest has shown that novel intra-sleep pulse oxymetry can be an effective modality in identifying cardiovascular disease risk in patients. In the study, a modified version of Weinmann‘s SOMNOcheck micro oximeter was used to observe pulse wave attenuation, heart rate acceleration, pulse propagation times, as well as respiration-related pulse oscillations and oxygen desaturation episodes. All the collected data was analyzed by an algorithm, and the prognostic results were checked against European Society of Hypertension/European Society of Cardiology (ESH/ESC) risk factor matrix.
Some details from the study abstract:

Methods: One hundred forty-eight sleep clinic patients (98 men, mean age 50 ± 13 years) underwent an overnight study using a novel photoplethysmographic sensor. CV risk was classified according to the European Society of Hypertension/European Society of Cardiology (ESH/ESC) risk factor matrix. Five signal components reflecting cardiac and vascular activity (pulse wave attenuation, pulse rate acceleration, pulse propagation time, respiration-related pulse oscillation, and oxygen desaturation) extracted from 99 randomly selected subjects were used to train the classification algorithm. The capacity of the algorithm for CV risk prediction was validated in 49 additional patients.
Results: Each signal component contributed independently to CV risk prediction. The sensitivity and specificity of the algorithm to distinguish high/low CV risk in the validation group were 80% and 77%, respectively. The area under the receiver operating characteristic curve for high CV risk classification was 0.84. β-Blocker treatment was identified as an important factor for classification that was not in line with the ESH/ESC reference matrix.

Abstract in Chest: Oximeter-Based Autonomic State Indicator Algorithm for Cardiovascular Risk Assessment
Product page: SOMNOcheck micro…
More from U of Gothenburg: Cardiovascular disease can be detected earlier during sleep…

descripimg SurgiVision MRI Compatible SmartFlow Cannula Receives FDA Clearance
SurgiVision has received FDA clearance for its MRI-Compatible SmartFlow Cannula, for use with the previously covered ClearPoint system (pictured above).
From the press release:

The SmartFlow cannula is an MRI-compatible injection and aspiration cannula for use in the brain. The SmartFlow cannula is compatible with SurgiVision’s ClearPoint® system. Using the new SmartFlow cannula with the ClearPoint system, neurosurgeons can select a neurological target, navigate the SmartFlow cannula to the target and observe the delivery of the therapeutic agent, all under intra-procedural MRI guidance. Other features of the SmartFlow cannula include a multi-step tip design to help prevent reflux along the cannula shaft.
“The medical community is continuing to find therapeutic agents that hold great promise in treating various CNS disorders, however many of these agents will require precision delivery, direct into a small neuro target,” said Kimble Jenkins, CEO of SurgiVision. “It is our hope that SurgiVision’s expanding range of products in interventional MRI could help fill this need and lead to better therapies for patients.”

At the same time, SurgiVision has also announced a collaboration with Brainlab, to bring the ClearPoint product line to that company’s iMRI interventional MRI suite. Aim of that collaboration is to enable local delivery of drugs and other therapeutic agents to precision targets in the brain under MRI guidance, in brain disorders such as Parkinson disease and malignant brain tumors.
Press releases: SurgiVision MRI-Compatible SmartFlow Cannula Receives FDA Clearance…, Brainlab and SurgiVision Announce Strategic Alliance in MRI-guided Drug Delivery and Other Interventional MRI Technologies in Neurosurgery…

vbq34 NeatClose: Lap Wound Closure at the Click of a Button
NeatClose is a sleek automated port closure device for laparoscopic entry wounds developed by an Israeli company NeatStitch Ltd. The tool, which already has FDA and European approvals, is marketed by the company as an4353gtoopp2 NeatClose: Lap Wound Closure at the Click of a Button alternative to manual closure, as a speedy and efficient way that will ultimately save time and money for surgeons and hospitals, by lowering intraoperative costs.

NeatClose is an easy to use, fully automated port closure system that allows surgeons to safely produce a watertight seal within seconds. Click on the video below to see a quick demonstration of how the system is prepared and used.
Once the system is prepared, NeatClose is easily inserted into the port. Once inside the operating cavity, the handle leavers can be squeezed to release two blunt needle guides. These guides are positioned perpendicular to the port plane, and put in firm contact with the peritoneum. The activation button is then pressed, which releases the needles from the guide, through the tissue and back to the NeatClose cartridge. The system is then pulled outside the port and the two presenting threads are tied in the standard fashion. An safe and eff icient air tight seal is created.


Product page: NeatClose …
(hat tip: Globes)

0h991utr Interpath Pathology Image Viewer Now on iPadRoom4, a company out of East Sussex, UK, has released its Interpath pathology slide viewing app for the iPad. Previously available only on the iPhone, the larger iPad screen makes browsing images much faster and more productive. The app relies on a slide scanner connected to a server from which relevant sections are transferred to the mobile device.

The application allows for a remote pathologist to review and navigate high quality images of diagnostic quality using either the cellular network or WIFI networks on the iPhone/iPad. Using the system rapid specialist referrals can be made, without access to a computer, a microscope or the original specimen. The image can be reviewed by the pathologist and used to provide a diagnosis used in cancer and other disease treatments.
The system which has been developed in collaboration with the Institute for Medical Informatics, IMI (Oslo) was first released in 2009 for the iPhone. It now supports fall versions of the iPhone, iPod Touch and iPad (Apple, US). The system allows for efficient mobile referrals using mobile devices and employs an efficient client server model, supporting many file formats in use for virtual microscopy.

Here’s a short demo video of the app on the iPhone:


Press release: Room4, announces presentation of the Interpath virtual microscopy application on the iPad 2…
Product page: Interpath for iPhone…
(hat tip: medtechinsider)

ak8w9ibm Tensio Blood Pressure Meter Design
Designer Diana Dumitrescu suggests a more aesthetic and less medical device-like look for a cuff blood pressure meter. The Tensio looks more like a fashion bracelet and would inflate the inside tube to create pressure just like a conventional BP meter.
yfnj1l3f Tensio Blood Pressure Meter Design
More at Yanko Design…