Archives: 1/2011

z277mvmk XWave EEG Brain Computer Interface for Your iPhone/iPad
The XWave is an EEG interface from PLX Devices (Sunnyvale, CA) that works with iPhones/iPads as a controller for games, meditation training, and potentially many other uses not invented yet. The actual EEG is NeuroSky‘s eSense dry sensor, which the company has been licensing to other companies in order to push the technology into consumer hands.
jwhwthh XWave EEG Brain Computer Interface for Your iPhone/iPad

The plastic headband, which costs around $100, has a sensor that presses against the user’s forehead and communicates with a free XWave iPhone application that then shows your brain waves graphically on the iPhone screen. As you focus your mind on a task the graphics are changed — a ball may move higher for instance, or your state of relaxation may be indicated by changes in a pulsating color, which moves towards blue as you become more relaxed.
Brainwave detection is powered by an NeuroSky eSense dry sensor, which provides a brain-computer interface (BCI) to sense even faint electrical impulses in the brain and convert them to digital signals that are sent to the iPhone. Previous applications of the NeuroSky technology include computer games and toys. In XWave an algorithm is applied to the brain rhythms to convert them to graphical representations of attention and meditation values.
XWave enables you to manipulate a number of other iPhone graphical applications and objects in games using only your brain waves, providing your rating in attention or meditation is high enough. At present you cannot text or browse the web using XWave, but you can use the device to train your mind to relax and focus on command. The list of applications for the device is likely to grow rapidly.

The XWave is meant to be used for entertainment, but can be applied to any other practical use, perhaps even as a controller for an assistive device for the disabled.


Product page: XWave…
Flashbacks: Video: Neurosky EEG Game Controller in Action; Coming Up: EEG Joystick; New Gaming Input Device Reads Your Mind; Brainwave Athletic Trainer Uses EEG to Improve Your Golf Swing

b34gsfgg Xpress Way RX Thrombus Extraction Catheter Launched in U.S.
Atrium Medical Corporation (Hudson, NH) and Kaneka Corporation (Osaka, Japan) have launched the Xpress-Way RX Extraction Catheter in the U.S. It is an extraction catheter for thrombi and emboli, both in the coronary and the peripheral arteries, featuring enhanced pushability and anti-kinking mechanisms. From the press release:

The Xpress-Way™ RX Extraction Catheter is an ultra low profile manual aspiration system designed for the removal of fresh, soft emboli, and thrombi in both coronary and peripheral vessels. Xpress-Way RX incorporates an innovative removable stylet and has been designed with enhanced pushability, anti-kinking, trackability, and crossability which allows for unmatched deliverability and market leading performance. Outside the United States, the Xpress-Way RX is marketed as the Thrombuster II (Kaneka Corporation, Osaka, Japan).

Press release: Atrium and Kaneka Launch Xpress-Way™ RX Extraction Catheter in the U.S….
Product page: Xpress-Way RX…

award lr The 2010 Medical Weblog Awards Sponsored by Epocrates and Lenovo

Welcome to the 2010 Medical Weblog Awards! It is time to celebrate and showcase the original reporting, engaging writing and discussion, breathtaking multimedia, and the spirit of community in the medical blogosphere. This is the seventh year of the competition and these awards are designed to highlight the exciting and useful role that the medical blogosphere plays in medicine and society. This year’s competition is sponsored by Epocrates® and Lenovo®.
epocrates on ipod touch The 2010 Medical Weblog Awards Sponsored by Epocrates and Lenovo
werwa The 2010 Medical Weblog Awards Sponsored by Epocrates and LenovoEpocrates® is generously donating the latest Apple iPod touch® to winners in each category, along with a subscription to the company’s most popular premium product for drug, disease, and lab information, Epocrates® Essentials clinical reference suite.
uybk65i0 The 2010 Medical Weblog Awards Sponsored by Epocrates and Lenovo
The grand prize winner in the Best Medical Weblog category will receive a brand new, lenovo logo The 2010 Medical Weblog Awards Sponsored by Epocrates and Lenovotop of the line Lenovo® Multi-Touch m90z ThinkCentre, an all-in-one model that Lenovo designed for professional use with medical applications strongly in mind. This powerful computer with a 23” full HD monitor was reviewed by Medgadget, and we were very impressed with its capabilities.
Additionally, the Best Medical Weblog category winner will receive Epocrates Online Premium reference, a premium drug and clinical reference for the web browser. Epocrates Online organizes practical, peer-reviewed drug and disease content with a unique patient-centered approach. The grand prize package is valued at over $2000.
pl23nf The 2010 Medical Weblog Awards Sponsored by Epocrates and LenovoAnd to wrap up the prizes, all winners will receive an annual subscription to the Placebo Journal, “The Only Medical Journal That Will Make You Laugh… On Purpose!” In the meantime, check out Placebo Journal’s blog.
Of course, bragging rights are the ultimate reward, and we wish everyone the best of luck!
The categories for this year’s awards are:

  • Best Medical Weblog
  • Best New Medical Weblog (established in 2010)
  • Best Literary Medical Weblog
  • Best Clinical Sciences Weblog
  • Best Health Policies/Ethics Weblog
  • Best Medical Technologies/Informatics Weblog
  • Best Patient’s Blog
  • Nominations are now accepted in the comments section of this post. When nominating, please indicate the blog’s name and URL, nominating category, as well as your thoughts why this particular blog deserves recognition. A blog can participate in more than one category, so please be precise which one(s). When we have all the nominees, Medgadget editors and Dr. Allen Roberts from GruntDoc will sort through all the blogs, and we will select up to five blogs in each category based on merit, and on our own internal voting results.
    The following time line will be observed:

  • Nominations will be accepted until 23:59:59 Sunday, January 23, 2011.
  • We will announce the finalists on Monday, January 24, 2011.
  • Polls will be open from Thursday, January 27, 2011 and will close at 23:59:59 EST on Sunday, February 13, 2011.
  • Winners will be announced on Friday, February 18, 2011.
  • Medgadget, as well as the individual blogs of our editors, are not eligible to participate in the awards.
    Voting for the awards will be open to all, but you will only be able to vote once. (No hacking or cookie manipulation will be tolerated — only one vote for each category from a particular IP address.)
    All final decisions will be made by our editors.
    Good luck to all!

    tgwer43 Electric Vagus Nerve Stimulation Shows Promise for Treatment of Noise Induced TinnitusResearchers from University of Texas at Dallas and spin-off company MicroTransponder Inc. are reporting in Nature a successful treatment of rats with tinnitus by using vagus nerve stimulation. MicroTransponder, a company still in a stealth mode, is working on a stimulator based on a technology called SAINT™ (Subcutaneous Array of Implantable Neural Transponders), a wireless neurostimulator thought to be effective for a range of conditions, such as pain management, stroke rehabilitation, tinnitus, and even anxiety. In the Nature study, investigators played sounds of specific frequency to the animals while vagus nerves were activated, and the team was able to effectively teach the brains of these rats to block out certain sounds altogether.

    For the VNS study, the research team used a “gap detection model” to document tinnitus in rats that were exposed to loud noise for one hour while under anesthesia. Each of the noise-exposed rats used in this study exhibited a significant impairment in the ability to detect a quiet gap in a tone near their tinnitus frequency, but exhibited no impairment when the gap was placed in a higher or lower tone.
    When the rats were exposed to VNS paired with sounds, the gap impairment was eliminated – indicating that the tinnitus was gone.

    Reportedly, human clinical trials are already planned for later this year.
    Full story from UT Dallas: Findings Show Promise in Battle Against Tinnitus…
    Abstract in Nature: Reversing pathological neural activity using targeted plasticity…
    MicroTransponder technology page…

    g5gv6fix Astronauts, Vigilance and Gorillas   Opening Session of STA 2011Medgadget editor Paul Pisklak, M.D., an anesthesia resident at Baylor, is attending the annual meeting of Society for Technology in Anesthesia. Here’s his first report.
    The keynote speaker at this year’s Society for Technology in Anesthesia conference at The Venetian in Las Vegas was Colonel Jim Bagian, M.D., P.E., a physician and astronaut. Dr. Bagian gave a talk cleverly entitled “Patient Safety: It’s Not Rocket Science.” His unique broad view of the aviation and healthcare industries gives him a special insight into the subject at hand.
    The main thrust of his argument is that a large percentage of adverse events that happen in hospitals are human and communication errors, i.e., misuse of the technology that we already have. One example he gave was from his former role as a VA safety official when a group of nurses came to him with an external pacemaker error. A patient was getting very bradycardic, but when they hooked up the pacemaker, it said “Error 004.” The nurses brought it to the hospital’s biomedical department staff, who simply took out and reinserted the battery. This workaround had been used for 8 years! Dr. Bagian ended up calling the manufacturer and addressing the root cause of the problem and having them update a software update. The gist of this story is the importance of addressing the root cause of device problems and not just “band-aid fixes.”
    Another interesting anecdote that he shared had to do with vigilance. A group of radar operators in the military was offered a full month’s extra pay if they could have 100% accuracy at detecting enemy ships. It turned out that despite the huge incentive, the operators’ accuracy went down considerably after an hour, demonstrating the human propensity to get distracted at routine tasks – a fact that has considerable applicability to anesthesiologists, who spend hours monitoring for what can be minuscule changes. Of note, providing electric shocks to the chairs of the radar operators every 10 minutes increased vigilance dramatically!
    Dr. Bagian drove this concept home with an interactive segment. To demonstrate the concepts of vigilance and “inattentional blindness,” he showed the following video. When you watch this, see if you can count how many times the ball is passed between people in white shirts.


    Now there’s food for thought about the things that we have to think about and those that we don’t.
    We will keep reporting from the STA conference…
    Dr. Bagian bio link…
    More info on inattentional blindness…

    GA Stanford Researchers Develop Video Games That Let You Interact With Microorganisms
    While the realism in today’s video games might create the impression that electronic characters are alive, a team of researchers at Stanford University has taken it a step further by creating “biotic games” which allow the player to actually interact with living organisms by controlling biological processes. The team has currently developed eight games similar to simple 1980s arcade titles which allow the player to control paramecium. While these biotic games are currently in the proof-of-concept stage, the researchers hope that eventually even people with little or no knowledge about biology will be able to participate in biomedical research just by playing more complex biotic entertainments. In a paper published in Lab on a Chip Stanford investigators mention that they hope to have "significant conceptual and cost-reducing effects on biotechnology and eventually healthcare; enable volunteers to participate in crowd-sourcing to support medical research; and educate society at large to support personal medical decisions and the public discourse on bio-related issues."
    From Stanford Report:

    The basic design of the games involving paramecia – the single-celled organisms used in countless biology experiments from grade school classes to university research labs – consists of a small fluid chamber within which the paramecia can roam freely. A camera sends live images to a video screen, with the "game board" superimposed on the image of the paramecia. A microprocessor tracks the movements of the paramecia and keeps score.
    The player attempts to control the paramecia using a controller that is much like a typical video game controller. In some games, such as PAC-mecium, the player controls the polarity of a mild electrical field applied across the fluid chamber, which influences the direction the paramecia move. In Biotic Pinball, the player injects occasional whiffs of a chemical into the fluid, causing the paramecia to swim one direction or another.


    Full text of the paper in Lab on a Chip: Design, engineering and utility of biotic games…
    Stanford Report coverage: Stanford researcher uses living cells to create ‘biotic’ video games
    (hat tip: Kotaku)

    Engineers at Rensselaer Polytechnic Institute (RPI) have developed capillarity-dominated technology where two adjoining ferrofluid droplets, called “liquid pistons”, saturated with metal nanoparticles oscillate and displace a surrounding liquid. Unlike their mechanical counterparts, these liquid pistons are highly tunable, scalable, and because they lack any solid moving parts, suffer no wear and tear.
    For the RPI study, researchers demonstrated the use of the liquid pistons as a tiny camera lens. Passing light through the droplets, one can move the droplets back and forth, changing the focal length and bringing and object into and out of focus.


    Moreover, as the droplets also displace the surrounding liquid, the liquid pistons could also act as micropumps and liquid switches for use in lab-on-chips or advanced drug delivery systems.
    Article @ RPI: “Liquid Pistons” Could Drive New Advances in Camera Lenses and Drug Delivery…

    41fasdf Vitality GlowCaps ReviewOur fellow bloggers at Engadget got their hands on a pre-release version of Vitality Glowcap and have been trying it out for about a month while keeping a diary of their experiences. They did some creative testing, amongst other things using it as an alarm clock and cheating their way out of taking the medications. Head over to the link below for the full story and the final judgment.
    Engadget: Vitality GlowCap review…
    Product page: GlowCaps…
    Flashbacks: Smarter Pill Bottle Caps; Internet Connected Bottle Caps Help Remember to Take Your Pills; Vitality GlowCaps Soon Easily Available for Purchase

    325432dow Multiplexed Maternal Plasma DNA Sequencing Effective to Safely Detect Down Syndrome in UnbornWhen doctors want to accurately test high-risk patients to determine whether their unborn babies will have Down syndrome, they currently perform karyotyping after an amniocentesis or chorionic villus sampling, procedures that have small chance of causing miscarriage. However, the Los Angeles Times reports that a team of researchers from China and the UK have proved that a much safer test can be effective in detecting trisomy 21. In a procedure similar to one we covered at Medgadget two years ago, the researchers analyzed fetal DNA which they recovered from maternal blood plasma to determine whether the baby would have Down syndrome.
    From Los Angeles Times‘ coverage:

    Using the new technology, researchers found they could rule out Down syndrome in 98% of cases, sparing the women from further testing. The blood test did not produce false negative results (showing the fetus did not have the disorder when, in fact, the condition was present).
    Currently, women in the United States are offered a blood test combined with an ultrasound test — called the combined test — to assess the risk of Down syndrome in pregnancy. The combined test still leaves an estimated 3% to 5% of women in need of invasive testing. The new blood test, which is conducted in the first trimester, could be used after the combined test or even as a first-tier test, said the study authors, from the Institute of Health Sciences in Hong Kong.

    Los Angeles Times Coverage: Prenatal blood test for Down syndrome shows high level of accuracy
    Full text of the study in the British Medical Journal: Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study
    Flashback: New Blood Test for Down Syndrome