Archives: 8/2009

kam3n32 Dean Kamen Offers Thoughts On Healthcare DebatePopular Mechanics recently asked Dean Kamen, one of the most prolific inventors with a penchant for medical devices, what he thinks about the current healthcare debate. Kamen’s basic argument is that the “crisis” of American healthcare is an overblown concept. To that end he points to the reality of technological progress in medicine and the ability to cure diseases that had no treatment options only a short time ago. As such, Kamen warns against spending cuts that may delay progress and lead to even greater spending in the future.
A tidbit from the PM interview:

Our healthcare system has seen some of the greatest achievements of the human intellect since we started recording history: We’re developing incredible devices and implantables to improve the quantity and quality of people’s lives. We’re developing pharmaceuticals that alleviate the need for surgery and eliminate the volatile effects of diseases. We’re making the surgeries that are necessary ever less invasive. You can get a stent through your femoral artery all the way up into your heart and fix a blockage without surgery. I’d say, if we have a crisis, it’s the embarrassment of riches. Nobody wants to deal with the fact that we’re no longer in a world where you can simply give everybody all the healthcare that is available.

We can’t agree with Dean Kamen any more than that. There is a reason why most of Medgadget archives cover devices and technologies coming from the United States. Here we have a great healthcare system, equipped with the latest technologies, smart doctors and clean hospitals. It might be an inefficient system, not covering everyone, but it is a system that delivers unbelievable technologies to help patients day in and day out. There must be a reason why we rarely see anything interesting coming out of France, Greece, Spain, Italy, or most other European countries (Germany being the clear exception).
Read the entire interview at Popular Mechanics: Inventor Dean Kamen Says Healthcare Debate "Backward Looking"…

trufocuse TruFocals Offer New Option For Presbyopic EyesDr. Stephen Kurtin, an inventor and a physicist with a degree from Caltech, has been working on adjustable eye glasses for the last two decades, trying to overcome the disadvantages of bifocals and progressive lenses. His work has finally led to a commercial product, called TruFocals, which features a slider above the nose bridge that changes the focal point of the lenses in real time. The glasses use a conventional lens co-axially paired with a distensible membrane, and a clear liquid resides between the two. The shape of the liquid can be adjusted precisely via the slider activated membrane, providing a selectable focal range that you can change depending on what you’re looking at.
Here’s Stephen Kurtin presenting the TruFocals:


Product page: TruFocals…
Review of TruFocals by John Markoff at the New York Times
Flashback: Water Power in Developing World to Cure Poor Eyesight

260xStory Where The Sun Never Shines: Under a PannusGeorge Vera, 25, was arrested last week for selling bootleg recordings on a street corner in Houston. Following at least four body searches of the suspect, authorities later booked Mr. Vera into the Harris County Jail. Turns out he managed to hide an unloaded 9mm pistol under a pannus in his massive body. Considering that a handgun recently appeared momentarily on the FDA rule books, we’ll consider this incident as an example of an implanted device.
The Houston Chronicle reports:

Police arrested Vera on Sunday after he was spotted selling apparently bootlegged compact discs out of the back of a sport utility vehicle parked at Hollister and Pitner, Hawkins said.
Police spokesman Victor Senties said Vera was searched three times by police personnel: once at the scene, again, more thoroughly, when he arrived at the city jail, and a final time before he was transferred to the Harris County Jail.
Vera was subjected to an additional search at the county lockup.
City and county law enforcement spokespeople said inmates at both the city and county jails are not required to pass through a metal detector or undergo wand searches.
Vera’s possession of the firearm came to light Monday when he approached a county guard during a shower break and admitted having smuggled the weapon, authorities said.

Perhaps he forgot about the gun and discovered it only when washing up all the nooks and crannies in the shower.
More at the Houston Chronicle: Gun found on obese inmate after 5 searches…

gggererer Nanoscale Origami from DNA SequencesScientists from Technische Universität München (TUM) and Harvard University have developed a method to use DNA sequences as a building blocks for three dimensional nanostructures. In the latest issue of Science, these investigators describe the various complicated forms that were “folded,” including a wireframe ball 50 nanometers in diameter.
From the press office at Technische Universität München:

"Our goal was to find out whether we could program DNA to assemble into shapes that exhibit custom curvature or twist, with features just a few nanometers wide," says biophysicist Hendrik Dietz, a professor at the Technische Universitaet Muenchen. "It worked," he says, "and we can now build a diversity of three-dimensional nanoscale machine parts, such as round gears or curved tubes or capsules. Assembling those parts into bigger, more complex and functional devices should be possible."
As a medium for nanoscale engineering, DNA has the dual advantages of being a smart material – not only tough and flexible but also programmable – and being very well characterized by decades of study. Basic tools that Dietz, Douglas, and Shih employ are programmable self-assembly – directing DNA strands to form custom-shaped bundles of cross-linked double helices – and targeted insertions or deletions of base pairs that can give such bundles a desired twist or curve. Right-handed or left-handed twisting can be specified. They report achieving precise, quantitative control of these shapes, with a radius of curvature as tight as 6 nanometers.
The toolbox they have developed includes a graphical software program that helps to translate specific design concepts into the DNA programming required to realize them. Three-dimensional shapes are produced by "tuning" the number, arrangement, and lengths of helices.
In their current paper, the researchers present a wide variety of nanoscale structures and describe in detail how they designed, formed, and verified them. "Many advanced macroscopic machines require curiously shaped parts in order to function," Dietz says, "and we have the tools to make them. But we currently cannot build something intricate such as an ant’s leg or, much smaller, a ten-nanometer-small chemical plant such as a protein enzyme. We expect many benefits if only we could build super-miniaturized devices on the nanoscale using materials that work robustly in the cells of our bodies – biomolecules such as DNA."

Press release: Nanoscale origami from DNA…
Abstract in Science: Folding DNA into Twisted and Curved Nanoscale Shapes

Art

winn3432 The Beauty of the Nanoworld Revealed at SPMage09
The International Scanning Probe Microscopy Image Contest 2009, featuring our beautiful world at a microscopic level, has just announced the winners of the competition. The submissions from around the world demonstrate how widespread the field of nanotechnology is, and the progress this field has achieved in only a few years.
Here are the five winners and their works above (left to right, top to bottom):

  • First Prize: Li Ang, National University of Singapore (Singapore)
  • Second Prize: Sander Otte, NIST-Center for Nanoscale Science and Technology (United States)
  • Third Prize: Sviatlana Abetkovskaia, A.V. Luikov Heat and Mass Transfer Institute (Belarus)
  • Fourth Prize: Francesco Mantegazza, Universita’ degli studi di Milano-Bicocca (Italy)
  • Fifth Prize: Mar Cardellach Redon, Centre d’Investigació en Nanociencia i Nanotecnologia (Spain)
  • Link: Gallery of submissions to the SPMAGE09 contest
    (hat tip: Nanowerk)

    jjj343 BLACKBAG For iPhone Keeps You In The Latest Info Loop
    Ortho-McNeil-Janssen Pharmaceuticals recently released a free iPhone application called BLACKBAG, primarily aimed at doctors, that provides the latest articles, as well as videos and podcasts of news stories and conference highlights. The goal is to provide busy physicians with an easy way to stay updated on the latest in the science of medicine.
    Product page: BLACKBAG™ for the iPhone…

    smartcane Smart Cane Helps Bring Rehab Out of Rehab
    To use a crutch properly after an injury is important if healing is to be promoted. However, monitoring a patient’s physiotherapeutic progress outside of the rehab center is next to impossible.
    Now, a physiotherapist and a computer scientist from the University of Southampton have teamed up to create an “intelligent crutch” that features force sensors and accelerometers. This smart crutch can provide info on its own movement and calculate the pressure that is applied to the leg. By processing the data, the device supposedly provides visual cues to the user when improper usage is perceived.
    More from the press office at University of Southampton: Intelligent crutch with sensors to monitor usage…
    (hat tip: The Engineer Online)

  • Governors Fear Added Costs in Health Care Overhaul… [NYT]
  • Researchers make stem cells from developing sperm… [Johns Hopkins]
  • Men with angina ‘at greater risk’… [BBC]
  • FDA smoke screen on e-cigarettes… [Washington Ttimes]
  • Doubts over stem cell images prompt new inquiry… [New Scientist]
  • France Fights Cost Of Universal Care … [WSJ]
  • FDA Chief: ‘Violations Have Gone Unaddressed for Far Too Long’… [WSJ]
  • FDA Commissioner Sets Out Vision on Enforcement to Support Public Health… [FDA]
  • Healthcare, the road to robotic helpers… [European Commission]
  • Medtronic Awarded $57 Million in Patent Dispute with AGA Medical Corporation… [Medtronic]
  • Impella sales pump up Abiomed… [MassDevice.com]
  • Sculpting an intricate x-ray nanofocusing lens out of diamond… [Nanowerk]
  • Tumor mutations can predict chemo success… [MIT]
  • Risk of Pancreatic Cancer Linked to Variation in Gene that Determines Blood Type… [NIH]
  • Scientists Find Cells Responsible for Bladder Cancer’s Spread… [Johns Hopkins]
  • Genomic Signature in Blood Identifies Underlying Viral Infection… [Duke]
  • Scientists find common trigger in cancer and normal stem cell reproduction… [Stanford]
  • Researchers identify itch-specific neurons in mice, hope for better treatments… [Washington University School of Medicine in St. Louis]
  • Staphylococcus epidermidis – the ‘accidental’ pathogen… [Nature Reviews Microbiology]
  • After the boom, is Wikipedia heading for bust?… [New Scientist]
  • Whole Foods CEO: ‘We Sell a Bunch of Junk’… [WSJ]
  • 0875tms1 VA to Trial Transcranial Magnetic Stimulation for ADDIsraeli business newspaper Globes is reporting that the U.S. Department of Veterans Affairs has signed an agreement with Brainsway, a Jerusalem company profiled by us many times before, to trial the firm’s deep transcranial magnetic stimulation (TMS) device on twenty patients with attention deficit disorder. Experts believe that TMS technology might become increasingly useful as a new way to treat a variety of psychiatric and neurological problems, such as bipolar disorder, cocaine or nicotine addiction, or even as a treatment for symptoms of Parkinson’s and multiple sclerosis.
    More about the upcoming trial from Globes
    Flashbacks: Brainsway to Test TMS for Smoking Cessation; Magnetic Brain Stimulation for Cocaine Addiction, Multiple Sclerosis?; Neuronetics TMS Depression Therapy Gets FDA OK; Experiencing Transcranial Magnetic Stimulation; Positive Results Reported for Deep TMS H System For Depression; Deep TMS Technology by Brainsway