Archives: 6/2009

OTC

smarthandle Doorknob With Auto Sleeve Refresher Keeps Contagions At Bay
We don’t like touching other people’s C.diff on bathroom door handles. As a matter of fact, even when visiting each other’s houses, we regularly find ourselves ripping an extra paper towel to grab the handle on a bathroom door, then fiddling with the feet to prop it open, and finally trying to masterfully throw the towel into the garbage bin located on the opposite wall. To stop all this silly juggling, Xela Innovations out of Milwaukee, Wisconsin has created a set of doorknobs that feature an automatic sleeve dispenser so that no two people touch the same handle twice
Here are features and benefits from the product page:

  • Advancing an antimicrobial-treated sleeve with every use, Purleve reduces the amount of disease-causing germs and bacteria, helping in the global fight against germ cross-contamination.
  • As part of an advanced automatic hygiene cycle, a Purleve handle proudly installed on the door helps to create a superior facility image, providing visitors assurance that they’re visiting a healthy environment within an establishment that caters to the well-being of their patrons.
  • Universality of design creates an unlimited global opportunity, with Purleve able to be easily retrofitted on any style of door worldwide.
  • The addition of Purleve—and the absence of costly wasted paper towels accumulating on the bathroom floor in a wet and dirty mess —makes visiting any public area a cleaner experience.
  • A simple interface and intuitive design strongly encourage compliance among users—particularly important in establishments that require more sanitary conditions.
  • Recyclable refills, an efficient power source and low power consumption provide an environmentally friendly solution that is globally beneficial… and universally understood.

  • Product page: Purleve hygienic door handles
    (hat tip: Gizmodo)

    biophotonics200b 21644546 The Latest On Laser Use in Medical ApplicationsThis week at the 19th International Congress on Photonics in Europe, a number of events relating to the use of lasers in medicine and the life sciences are taking place. Medical Physics Web has a rundown of some of the technologies from today’s presentations. Specifically, MPW gives focus to photodynamic therapy (PDT), optical coherence tomography (OCT), and the use of “a backscattered light detector (BLD) for visualizing tissue coagulation during MRI-assisted interstitial laser thermotherapy (ILTT).”
    Read: Lasers make their mark in medicine…
    Link: BIOPHOTONICS AND LIFE SCIENCES at LASER World of PHOTONICS 2009

  • President Obama’s speech to American Medical Association… [President Obama]
  • Doctors’ boos show Obama’s tough road… [AP]
  • Medicare advisers eye imaging, biologics savings… [Reuters]
  • Congress Invests in Health Care… [WSJ]
  • VA inspections show continued flaws… [AP]
  • FDA Issues Safety Communication about an Ongoing Review of Stimulant Medications Used in Children with ADHD… [FDA]
  • FDA Issues Public Health Advisory Regarding Levemir Insulin… [FDA]
  • St. Jude Medical Announces Leading Sponsorship of Landmark Clinical Trial to Study Atrial Fibrillation… [St. Jude Medical]
  • The Fable of the Dragon-Tyrant… [Nick Bostrom]
  • TRAPping proteins that work together inside living cells… [Pacific Northwest National Laboratory]
  • Researchers Discover How Prion Protein Damages Brain Cells… [NIH]
  • Bill Gates helps fund mass circumcision programme… [New Scientist]
  • Alcohol’s Good for You? Some Scientists Doubt It… [NYT]
  • More doctor’s prescriptions may include brain games to improve mental acuity… [USA Today]
  • stopm324 Motion Frozen Technology Takes The Blur Out of PET
    Even though positron emission tomography has been a popular oncology imaging tool for years, the quality in this technique does suffer when scanning moving organs like the heart. To overcome the blurring of the image, researchers at Cedars-Sinai Medical Center in Los Angeles have used in-house developed “motion-frozen” technology in combination with a Siemens high definition PET scanner to spot myocardial defects that would otherwise have been invisible.
    From a statement by the Society of Nuclear Medicine on the study presentation at the 56th Annual Meeting:

    The high-definition PET scanner uses "spatially variant detector spatial response" when the image is reconstructed, correcting for distortion and noise that can make images hard to interpret. The motion-frozen technology, originally developed by Piotr Slomka, research scientist at Cedars-Sinai Medical Center, is an image-processing technique that compensates for the motion of the beating heart. It removes unwanted blur and thus improves the diagnostic value of imaging.
    In the study, the combined technologies were used to obtain images of ten patients who were referred for PET myocardial viability assessments at Cedars-Sinai Medical Center. For these patients, the diagnostic results were modified after imaging with the new technologies—sometimes drastically. By combining high-definition PET and motion-frozen technology, the resulting cardiac PET images provided physiological details that were previously hidden from physicians.
    Researchers are investigating expanding this technique to correct for the distortions that arise from respiratory motion during imaging.

    Press release: "Motion-Frozen" Technology Meets High-Definition PET: Helping Heart Patients
    Image: MF-HD*PET detected an apical inferior defect (red arrows) not visible without the use of this image processing technique.

    breastring PET/MRI Combination Might Improve Breast CA Visualization
    Brookhaven National Laboratory researchers are developing a new imaging modality that combines PET and MRI to help identify abnormalities within breast tissue. The PET detection ring shown above would fit inside an MRI scanner and the two would complement each others’ data streams for better visualization. The new technology is being unveiled this week at the Society for Nuclear Medicine 56th Annual Meeting in Toronto, Canada.
    From the Society for Nuclear Medicine:
    ba234234 PET/MRI Combination Might Improve Breast CA Visualization

    When completed, the dedicated breast PET-MRI system will consist of a modular 3D tomographic PET scanner that is inserted inside a dedicated breast MRI coil produced by Aurora Technologies, Inc allowing both PET and MRI images to be taken simultaneously. The modularity of the PET system would allow for the scanner diameter to be adjusted according to patient breast size. Researchers expect the combined modality scanner will provide anatomical information from the MRI to enhance the resolution provided by PET. At the same time, the predictive power of PET in identifying the type of tumor should be able to overcome MRI technology’s traditionally high false-positive rates.
    Based on the positive preliminary results, researchers expect to begin testing the system shortly with breast cancer patients.

    Press release: Prototype Breast Cancer Imaging System May Improve Patient Care

    spiderside Spiderman Your Way Down During Hospital FiresHospital fires are not an uncommon occurrence, as one of our editors has learned having to evacuate his patients twice within just a few short months. As hospitals have become bigger and taller, the potential of dispersed people becoming trapped on different floors is only growing. Spider International, a small company out of London, UK, has developed a compact evacuation system that can rapidly bring people down to Earth on a steel cable.

    The Spider Lifeline to Safety can save lives when staircases and fire exits have become impassable, or circumstances such as disability make using conventional exits impossible. It comes in to its own as a last resort and can save your life.
    The ground-breaking device employs fall-arrest technology to lower people to safety down the exterior of a building using a harness and strengthened steel cable. The system allows users to descend at a regulated speed ensuring a quick exit to safety, at a pace that does not endanger the user or other people evacuating the building.
    Spider Lifeline to Safety is suitable for use in all buildings providing safe exit from any height whether a two storey
    house or a 50 storey office building. The device is capable of multiple evacuations, with adults able to carry their
    children and a fast return of the harness to the evacuation point for immediate re-use.
    The Spider Lifeline to Safety has been designed to work in all conditions and does not need any external power
    source for operation. The Spider Lifeline to Safety has been rigorously tested and also includes an emergency
    braking system as well as a double security mechanism for maximum safety.

    Spider Lifeline product brochure
    Spider International homepage
    Flashbacks: Evacuate Babies Efficiently with BabyScatt; Evacusled for Efficient Hospital Evacuations; Emergency Evacuation Chair, Bed
    Artículo Medgadget Original en Inglés

    Neuroscientists from Johns Hopkins University are using total internal reflection fluorescence microscopy to essentially watch physical neural processes as memories form. Their observations have uncovered that a protein called 4.1N helps the AMPA receptor protein form connections in the brain that are responsible for our memories. Because the involvement of 4.1N was not known before, the new knowledge may help in developing diagnostic tests and treatments for memory disorders like Alzheimer’s.
    From Johns Hopkins:

    The research team first attached fluorescent tags to AMPA receptor proteins in rat neurons growing on glass slides. Using a laser, they first photobleached the cells to prevent anything from glowing except for newly inserted proteins. When they looked at the slides under a microscope they saw dots appearing on the surface of the neurons, which they interpreted to be the AMPA receptors being inserted into the cell’s surface.
    “In the past it was like looking for a shooting star in a bright, night sky full of other stars,” says neuroscience research associate Da-Ting Lin, Ph.D. “Ideally you need a dark sky to clearly see that shooting star, and we’ve now made our dark sky and are starting to find our shooting stars.”
    They then asked what other proteins might be leading AMPA receptors to where they should be once they reach the cell’s surface. To do this, they chopped a short bit off the end of the AMPA receptor, put it into neurons and watched the cells under the microscope to see if those same dots appeared. After cutting off more and more and testing each version, they finally ended up with an AMPA receptor that was not inserted into the cell surface. It turns out they had cut off the region of AMPA receptor known to bind another protein, called 4.1N.
    “We knew that 4.1N and related proteins can bind to the cell’s skeleton as well as to proteins at the cell surface, but we never knew what role 4.1N played in AMPA receptor movement,” says Lin.
    To see if 4.1N is critical for forming memories, the team stimulated neurons and measured electrical connections—signs of memory formation—from neurons containing and missing 4.1N. Neurons containing 4.1N had sustained strong electrical connections while neurons missing 4.1N initially had strong electrical connections but they weakened after 30 minutes.
    “Normally, this type of neuronal stimulation makes the cell connections stronger,” says Lin. “But in cells missing 4.1N we see an initial strong connection but it doesn’t hold. So we think 4.1N is required to keep the strong connection going, and therefore make the memory stick.”

    Here are clips visualizing AMPAR Insertion with TIRF imaging:


    AMPAR Insertion and Diffusion on dendrites, high resolution. Magenta: dendrite and spines morphology; Green: Insertion of AMPAR:

    Press release: JOHNS HOPKINS NEUROSCIENTISTS WATCH MEMORIES FORM IN REAL TIME

    can3top Canon Releases Two Video Projectors Featuring DICOM Mode
    To properly display X-rays and other medical imagery, DICOM compliant monitors are able to output grayscale with a greater precision than consumer screens. Last week Canon has released two new projector models that feature a DICOM output mode that should be of help in large medical school halls and at academic hospital colloquia.

    These products feature a DICOM Simulation mode for compliance with the Digital Imaging and Communications in Medicine (DICOM) Part 14 standardized display function for display of grayscale images. This new mode will provide medical educators with greater flexibility when training and conducting lectures and conferences where a large display is needed. The two projectors are not cleared or approved for medical diagnosis and should not be used for these purposes.
    The addition of the DICOM Simulation mode on both the Canon REALiS WUX10 Mark II D and REALiS SX80 Mark II D Multimedia Projectors will allow users in the medical education industry to have high-resolution images with exceptional detail and clarity. Both multimedia projectors will feature the LCOS technology found on all REALiS models to provide medical educators with the ability to display film-like X-Rays to large audiences in lecture halls, while also displaying ultra-smooth, lattice-free images.

    can4bot Canon Releases Two Video Projectors Featuring DICOM Mode

    Both new multimedia projectors will allow the user to calibrate directly on the projector rather than having to purchase additional equipment. Canon’s DICOM Simulation mode offers 21 different levels of grayscale gradation for greater flexibility when calibrating in a classroom, conference room or any other venue where a large display is required and the ambient light can vary.
    The Canon REALiS WUX10 Mark II D Multimedia Projector will feature a native WUXGA resolution (1920 x 1200) with a 2.30-megapixel display, while the REALiS SX80 Mark II D Multimedia Projector will have a native SXGA+ resolution (1400 x 1050) with a 1.47-megapixel display. With the additions of these projectors, Canon has further enhanced its total medical education solution from input (digital X-ray image acquisition) to output (projection).

    Press release: CANON U.S.A. ANNOUNCES NEW HIGH-RESOLUTION LCOS PROJECTORS WITH DICOM SIMULATION MODE FOR USE IN MEDICAL EDUCATION
    Product pages: REALiS WUX10 Mark II D; REALiS SX80 Mark II D

    secatop New Pediatric Offerings from seca
    seca, an old German scale maker based out of Hamburg, has released a few new products for the pediatrician’s office, including a versatile digital scale, an infantometer, and a portable stadiometer to measure entire little league teams off the field.
    From the German Healthcare Export Group:
    secoside New Pediatric Offerings from seca

    In one easy step the seca 384 baby scale can be converted into a flat scale on which toddlers can stand to be weighed. All the user has to do is press a key to release the lock on the removable weighing tray. When the tray is fixed on the base, its gently rounded shape and high sides give even the smallest babies a feeling of security. To determine the amount of milk an infant has consumed, the user weighs the baby before and after breast-feeding and activates the Breast Milk Intake Function (BMIF), which automatically calculates and displays the difference in weight. The TARE function can deduct the weight of a towel placed in the weighing tray with the baby. The Auto-HOLD function guarantees that the weight remains displayed until after the child has been tended to. In calibration Class III, the seca 384 can weigh up to 20 kilograms. The scale weighs up to 10 kilograms in 10 grams graduations, and beyond that, in 20 grams graduations.
    The seca 417 Infantometer measures the exact length of a child while lying down. The user unfolds the two-piece measuring board and attaches the foot positioner. High sides and a stable head positioner ensure that the child is properly placed. The large foot positioner glides smoothly along the measurement scale on guide rails to the bottom of the child’s feet. The length can be easily read from the red scale, which has a range of 10 to 100 cm.
    For transport the foot positioner is loosened, slid next to the head positioner and fixed into place by folding up the bottom element on the measuring board. The seca 417 is conveniently stored with the seca 384 scale in the seca 414 carrying case and then easily carried to the next place of use.
    The seca 437 adapter connects the seca 217 stadiometer to the seca 877 electronic flat scale to make up a complete weighing and measuring station for adults and schoolchildren. Weighing and measuring can take place in a single step anywhere. Between uses the individual elements of the stadiometer can be taken apart and safely transported along with the scale and adapter in the seca 414 carrying case.
    With a quick tap on the platform, the seca 877 flat scale is immediately ready for use. The scale’s integrated 20-millimeter-high display shows the precise weight. The Class III calibrated seca 877 weighs persons up to 200 kilograms. The graduation is 100 grams up to 150 kilograms and 200 grams at higher weights. With the help of a level and four large leveling bases, the scale can be set up correctly and securely at each new location.
    When a small child is weighed in its mother’s arms, the previously stored weight of the mother is deducted from the total, leaving only the child’s weight in the display.

    seca3423 New Pediatric Offerings from seca
    Product pages: stadiometer seca 217; seca 384/385 baby scales; seca 417 infantometer
    Link @ German Healthcare Export Group: Mobile Weighing and Measuring Systems…